| Exit | Roads | City | Hotels |
| 0 | Interstate 5, MLK Jr. Blvd | Portland | |
| 1 | Lloyd Center, 16th Drive, 33rd Avenue | Portland | ★★★★★ DoubleTree by Hilton Hotel Portland |
| 2 | 39th Avenue, 43rd Avenue | Portland | |
| 3 | 60th Avenue | Portland | |
| 4 | Halsey St, 68th Avenue | Portland | |
| 5 | OR 213 (82nd Avenue) | Portland | |
| 6 | I-205 (south) | Portland | |
| 7 | Halsey Street | Portland | |
| 8 | I-205 (north) | Portland | |
| 9 | 102nd Avenue | Portland | |
| 9 | I-205 | Portland | |
| 10 | 122nd Avenue | Portland | |
| 13 | 181st Avenue | Portland, Gresham | ★★★★★ Courtyard Portland East ★★★★★ Four Points by Sheraton Portland East ★★★★★ Hampton Inn Portland East |
| 14 | 207th Avenue, Fairview Pkwy, to US 30 | Fairview | |
| 16 | 238th Drive | Troutdale | ★★★★★ Best Western Plus Cascade Inn & Suites ★★★★★ Travelodge by Wyndham East Portland/Gresham |
| 17 | Marine Drive, 257th Avenue | Troutdale | ★★★★★ Holiday Inn Express Portland East - Troutdale ★★★★★ Comfort Inn Troutdale |
| 18 | Crown Point Hwy, Lewis and Clark State Park | Troutdale | |
| 22 | Corbett Hill Rd | Corbett | |
| 25 | Rooster Rock State Park | ||
| 28 | Historic Columbia River Highway | Bridal Veil | |
| 29 | Dalton Point (Benson State Park) | ||
| 30 | Benson State Park | ||
| 31 | Multnomah Falls | ||
| 35 | Historic Columbia River Highway, Ainsworth State Park | ||
| 37 | Warrendale | ||
| 40 | Bonneville State Park | ||
| 41 | Eagle Creek National Fish Hatchery, Eagle Creek Loop | ||
| 44 | US 30 | Cascade Locks | ★★★★★ Best Western Plus Columbia River Inn |
| 47 | Forest Lane, Wyeth Road | ||
| 51 | Wyeth Road | ||
| 55 | Starvation Creek State Park | ||
| 56 | Viento State Park | ||
| 58 | Mitchell Point Overlook | ||
| 62 | US 30 (Cascade Ave) | Hood River | ★★★★★ Holiday Inn Express & Suites Hood River |
| 63 | 2nd Street | Hood River | ★★★★★ Hampton Inn & Suites Hood River |
| 64 | US 30 (Mount Hood Highway) | Hood River | ★★★★★ Best Western Plus Hood River Inn |
| 69 | US 30 | Mosier | |
| 72 | Memaloose State Park | ||
| 76 | US 30 | Rowena | |
| 82 | River Road, to US 30 | The Dalles | |
| 83 | US 30 | The Dalles | |
| 84 | US 30 (2nd St, Weber St) | The Dalles | ★★★★★ Holiday Inn Express & Suites The Dalles ★★★★★ Fairfield Inn & Suites The Dalles ★★★★★ Travelodge By Wyndham The Dalles ★★★★★ Super 8 by Wyndham The Dalles |
| 85 | US 30 (2nd St) | The Dalles | |
| 87 | US 30, US 197 | The Dalles | ★★★★★ Columbia River Hotel, Ascend Hotel Collection ★★★★★ Comfort Inn Columbia Gorge The Dalles |
| 88 | The Dalles Dam | ||
| 97 | OR 206, Celilo Park | ||
| 104 | US 97 | Biggs Junction | |
| 109 | John Day Dam Road | Rufus | |
| 112 | John Day Dam | Rufus | |
| 114 | LePage Park | ||
| 123 | Quinton Canyon Rd | ||
| 129 | Blalock Canyon Rd | ||
| 131 | Woelpern Road | ||
| 137 | OR 19 (Locust St) | Arlington | |
| 147 | OR 74 (Heppner Hwy) | ||
| 151 | Threemile Canyon Rd | ||
| 159 | Tower Road | ||
| 164 | Main Street | Boardman | ★★★★★ Sleep Inn Boardman ★★★★★ Rodeway Inn Boardman |
| 165 | Laurel Lane, Port of Morrow | Boardman | |
| 168 | US 730 | ||
| 171 | Paterson Ferry Road | ||
| 177 | Umatilla Army Depot | ||
| 179 | I-82 | ||
| 180 | Westland Road | Hermiston | |
| 182 | OR 207 (Hermiston Hwy) | Hermiston | ★★★★★ Comfort Inn & Suites Hermiston |
| 188 | US 395 (Umatilla-Stanfield Hwy) | Stanfield | |
| 193 | Echo Road | ||
| 198 | McClintock Road, Lorenzen Road | ||
| 199 | Yoakum Road | ||
| 202 | Barnhart Road | ||
| 207 | US 30 (Westgate, Murietta Rd) | Pendleton | ★★★★★ Radisson Hotel Pendleton Airport |
| 209 | US 39, OR 37 (Emigrant Ave, Southgate) | Pendleton | |
| 210 | OR 11 | Pendleton | ★★★★★ Hampton Inn Pendleton ★★★★★ Holiday Inn Express Pendleton ★★★★★ Best Western Plus Pendleton Inn ★★★★★ Super 8 by Wyndham Pendleton |
| 213 | US 30 (Pendleton Hwy) | Pendleton | |
| 216 | OR 331 (Market Rd) | ||
| 224 | Poverty Flat Road, Old Emigrant Hill Road | ||
| 228 | Deadman Pass, Evergreen Lane | ||
| 234 | Emigrant Spring State Park | ||
| 238 | Old Hwy 30 | Meacham | |
| 243 | Summit Road | ||
| 248 | Spring Creek Road | ||
| 252 | OR 244 (Hilgard Hwy) | Hilgard | |
| 256 | Perry | Perry | |
| 257 | Perry | Perry | |
| 259 | US 30 | La Grande | |
| 261 | OR 82 (Island Ave) | La Grande | ★★★★★ Hampton Inn and Suites by Hilton La Grande ★★★★★ Best Western Plus Rama Inn & Suites ★★★★★ Super 8 by Wyndham La Grande |
| 265 | US 30, OR 203 (Adams Ave) | ||
| 268 | Foothill Road | ||
| 270 | Ladd Canyon Road | ||
| 273 | Frontage Road | ||
| 278 | Clover Creek | ||
| 283 | Wolf Creek Lane | ||
| 285 | US 30, OR 237 (2nd St) | North Powder | |
| 298 | OR 203 (Medical Springs Hwy) | ||
| 302 | OR 86 | Baker City | |
| 304 | OR 7 (Campbell St) | Baker City | ★★★★★ Best Western Sunridge Inn & Conference Center ★★★★★ Super 8 by Wyndham Baker City ★★★★★ Rodeway Inn Baker City |
| 306 | US 30 | ||
| 313 | Old US 30, Pleasant Valley | ||
| 317 | Old US 30, Pleasant Valley | ||
| 327 | Durkee Road | Durkee | |
| 330 | Cement Plant Road, Plano Road | ||
| 335 | Weatherby | ||
| 338 | Lookout Mountain Road | ||
| 340 | Rye Valley Lane | ||
| 342 | US 30 (Huntington Highway) | Lime | |
| 345 | US 30 | Huntington | |
| 353 | US 30 (Huntington Highway) | ||
| 356 | OR 201 | ||
| 362 | Moores Hollow Road | ||
| 371 | Stanton Boulevard | Ontario | |
| 374 | OR 201 (US 30 Bus. east) | Ontario | |
| 376A | US 30 Bus. West (Idaho Ave) | Ontario | ★★★★★ Holiday Inn Express Hotel & Suites Ontario ★★★★★ Super 8 by Wyndham Ontario |
| 376B | US 30 east (Idaho Ave) | Ontario | ★★★★★ Holiday Inn Ontario ★★★★★ Best Western Plus Inn & Suites ★★★★★ Quality Inn Ontario ★★★★★ Sleep Inn Ontario ★★★★★ Rodeway Inn Ontario |
| (mile 377 - Idaho stateline) | |||
| Interstate 84 in Idaho |