The Holiday Inn Express hotel in Bishop is a long, thin building at 636 Main St, just south of the city park and an easy walk from all necessary amenities in the town center including various restaurants and a supermarket. An indoor pool, sauna fitness center & guest laundry are the main amenities, plus a refrigerator, microwave & free high speed internet access in every room and suite. Complimentary continental breakfast is served.

At 1025 N Main Street, the Best Western Bishop Holiday Spa Lodge is situated along the main road through Bishop, just opposite the main supermarket/shopping area in town, and adjacent to several restaurants. Some of the 89 rooms have views westwards over the Sierra Nevada, while others look north towards the volcanic tableland that marks the north end of Owens Valley. The hotel has a sheltered outdoor pool, away from the road, an indoor bbq/picnic area, guest laundry, and refrigerator/microwaves in each room; free continental breakfast is provided.

Right in the center of Bishop, Best Western Creekside Inn is a large building alongside Bishop Creek, at 725 N Main St, almost opposite the Holiday Inn Express, and offers 89 rooms on 2 floors in a pleasant setting surrounded by trees and gardens. The stream runs right through the hotel grounds, and many rooms have views over the water from patios or balconies. The hotel has an outdoor heated pool, reached by a bridge over the creek, and serves complimentary breakfast. There are at least 5 restaurants within 1/4 mile.

Comfort Inn Bishop is another motel along Main St (US 395) through the center of town, offering 89 north or south-facing rooms on 2 floors linked by exterior corridors, with an outdoor pool at one side, away from the road. There are several shops adjacent to the inn, and a good selection of restaurants. Amenities include free continental breakfast, guest laundry and a refrigerator in each room.