Click on a city for full hotel listings and location maps, or a hotel for reservations. The hotels featured are either right beside the interstate exit or at most half a mile from it. 164 miles of I-10 pass through New Mexico, from southeast Arizona to west Texas.
All New Mexico interstates: I-10, I-25, I-40.
All New Mexico interstates: I-10, I-25, I-40.
Please refer to the disclosure notice for information about the affiliate (commissionable) links on this page.
| Exit | Roads | City | Hotels |
| Interstate 10 in Arizona | |||
| (mile 0 - Arizona state line) | |||
| 3 | Steins Road | ||
| 5 | NM 80 | ||
| 11 | NM 338 | ||
| 15 | Gary | ||
| 20 | I-10 Bus (Motel Drive) | Lordsburg | ★★★★★ Days Inn & Suites by Wyndham Lordsburg |
| 22 | NM 494 (Main Street) | Lordsburg | ★★★★★ Hampton Inn Lordsburg ★★★★★ Comfort Inn & Suites Lordsburg ★★★★★ Econo Lodge Lordsburg |
| 24 | I-10 Bus (Motel Drive), US 70 | Lordsburg | |
| 29 | (ranch exit) | ||
| 34 | NM 113 | ||
| 42 | Separ | ||
| 49 | NM 146 | ||
| 55 | Quincy | ||
| 62 | Gage | ||
| 68 | NM 418 | ||
| 81 | I-10 Bus (West Pine Street) | Deming | ★★★★★ Best Western Deming Southwest Inn ★★★★★ Comfort Inn & Suites Deming |
| 82A | US 180 to NM 26 (Gold Avenue) | Deming | |
| 82B | Cedar Street, Railroad Boulevard | Deming | ★★★★★ Baymont by Wyndham Deming ★★★★★ Days Inn by Wyndham Deming |
| 85 | I-10 Bus (East Pine Street) | Deming | ★★★★★ Hampton Inn-Deming ★★★★★ Holiday Inn Express Hotel & Suites Deming Mimbres Valley ★★★★★ Quality Inn Deming |
| 102 | Akela | ||
| 116 | NM 549 | ||
| 127 | Corralitos Road | ||
| 132 | Las Cruces Airport | Las Cruces | |
| 135 | US 70 (West Picacho Avenue) | Las Cruces | |
| 139 | NM 292 (Motel Boulevard) | Las Cruces | |
| 140 | NM 28 (Avenida de Mesilla) | Las Cruces | ★★★★★ Hampton Inn & Suites Las Cruces I-10 ★★★★★ SpringHill Suites Las Cruces ★★★★★ Comfort Inn & Suites Las Cruces ★★★★★ Days Inn by Wyndham Las Cruces |
| 142 | NM 101 (University Avenue), NM 188 (Valley Drive), NM 478 (Main Street) | Las Cruces | ★★★★★ Courtyard Las Cruces at NMSU ★★★★★ Holiday Inn Express Hotel & Suites Las Cruces ★★★★★ Quality Inn & Suites Las Cruces ★★★★★ Econo Lodge Las Cruces ★★★★★ Super 8 by Wyndham Las Cruces University Area |
| 144 | Interstate 25 | Las Cruces | |
| 151 | NM 228 | Mesquite | |
| 155 | NM 227 (Vado Drive) | Vado | |
| 162 | NM 404 (Ohara Road) | Anthony | |
| (mile 164 - Texas state line) | |||
| Interstate 10 in Texas | |||
| (13) | Sunland Park Drive | Sunland Park | ★★★★★ The Hotel at Sunland Park Casino, Ascend Hotel Collection |
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