For a small town, Ouray has a fair selection of hotels. The Best Western Twin Peaks Lodge (125 3rd Ave) is at the southwest corner of Ouray, close to the Uncompahgre River, the Hot Springs and scenic Box Canyon Falls. All 56 rooms enjoy views of the high, forested slopes of the San Juan Mountains that enclose the town on both sides, as does the outdoor pool and the two hot tubs, fed by natural spring water. The hotel serves free full breakfast, while for other dining there are at least 6 restaurants within a few blocks.

The Comfort Inn hotel in Ouray, at 191 5th Ave, is a rustic lodge with 33 mountain-view rooms, and is centrally placed for all of Ouray's natural attractions: Cascade Falls, Ouray Hot Springs and Box Canyon Falls are just some of the sites within walking distance. The hotel has a hot tub, sun deck & guest laundry, and serves free full breakfast.