New for 2008, Marriott's SpringHill Suites is another hotel on the southwest side of Lancaster close to highway 14, seven miles north of the adjacent town of Palmdale. Accommodation comprises 94 modern studio suites that include a kitchenette (sink, refrigerator, microwave, coffee maker), plus a large work desk, extra sofa bed, and separate living/sleeping areas. Free breakfast is served, an on-site store sells basic snacks, and there are several restaurants one block south, along W Avenue K. A hot tub, exercise room and pool allow guests to relax in this hot desert environment.

The Holiday Inn Express is one of the newest hotels in Lancaster, located along highway 14 on the west edge of town where most of the large stores are found, including the Lancaster Marketplace Mall a mile to the north. The inn is a medium sized building of 3 floors and 73 rooms - overlooking either the freeway or a housing district - an outdoor pool & hot tub, health & fitness center and a breakfast bar. The hotel is well placed for travelers between Los Angeles and the Mojave Desert or Owens Valley.

Comfort Inn & Suites is part of a business district with hotels, stores & restaurants either side of highway 14 on the west side of Lancaster - the 58 room, interior corridor property is right next to the freeway, half way between the Avenue K and Avenue J8 exits. The main guest amenities are an outdoor pool/hot tub, sauna, guest laundry, free continental breakfast and a microwave/refrigerator in each room. There are 2 restaurants adjacent.