Although aimed mostly at business travelers to the surrounding Kearny Mesa industrial park - nearby company offices include Lockheed Martin, Northrop Grumman and Jack in the Box - the full service Courtyard San Diego Central is well connected to all other area attractions via the adjacent 163 Freeway (accessed from the Clairemont Mesa Blvd exit) that links with I-15 and I-805. The well-regarded hotel has 245 rooms, an all-day restaurant, coffee shop, lounge bar, 24 hour convenience store, hot tub, fitness center, and quite a large outdoor pool, in the middle of the courtyard garden. For meetings & events there are 5 rooms, totaling 4,000 sq ft of space.

The apartment-style Residence Inn San Diego Central contains 144 suites in 9 adjacent blocks, providing high quality extended stay accommodation, with room amenities including a full kitchen, modern work station, extra sofa bed, and separate living/sleeping areas. The inn is 8 miles north of downtown San Diego at the junction of Clairemont Mesa Blvd with Highway 163 - in the middle of the Kearny Mesa business park, and close to the empty, hilly land of the Miramar Marine Corps Air Station. There are a few restaurants close by, though a free evening supper is provided weekday evenings (plus beer/wine), and free hot breakfast is served every morning. For relaxation the Residence Inn has the expected facilities of outdoor heated pool, whirlpool and fitness center.