The 79 room Holiday Inn Express hotel in Sorrento Valley caters primarily for business travelers to the Miramar - Sorrento area, location of dozens of company buildings, though the nearby 805 Freeway puts guests within easy reach of all other San Diego attractions. The clean, new-looking inn is 2 blocks east of I-805 exit 27 (Mira Mesa Blvd), and 3 miles north of the Miramar Marine Corps Air Station. Complimentary services are continental breakfast, high speed internet access, parking and a 5 mile local area shuttle; other amenities include an outdoor pool, whirlpool, fitness center, business center and one meeting room.

Half way between interstates 5 & 15, the Staybridge Suites in Sorrento Mesa is well positioned for visitors to the many technology companies based in the surrounding Sorrento Valley. The hotel is just off the main road through the area (Mira Mesa Boulevard), right next to a shopping center with many restaurants, but facing away from the main road for a more peaceful atmosphere. Many of the 131 suites, on 4 floors, have views over the hotel's well kept courtyard garden with fountain, outdoor pool, sports court and bbq grills. All the suites contain a full kitchen including a dishwasher; other guest amenities are a convenience store, fitness center, laundry, staffed business center, free 5 mile local area shuttle, free breakfast (continental), and a meeting room.

The Sorrento Mesa Courtyard hotel is a part of the extensive business district centered around Mira Mesa Blvd, and within easy reach of the neighboring towns of La Jolla, University City, Del Mar & Miramar. It is also one of the closest hotels to Torrey Pines (6 miles), as well as being within easy reach of all central San Diego attractions via I-805 which runs by 2 blocks west. As expected for a Courtyard property the 149 rooms are modern, spacious and immaculately clean, as are the public areas, which here include a cafe (serving breakfast only), guest laundry, 2 meeting rooms, a 24 hour fitness center and the beautiful garden containing a pool, hot tub and many tropical plants.

Another hotel in the Sorrento Mesa business/industrial park, the Residence Inn by Marriott caters to long stay visitors or those needing the extra space and amenities of a suite; the 150 rooms have separate areas for sleeping, living and cooking - the latter in a full kitchen that includes a dishwasher, microwave, stove and refrigerator. Free hot breakfast buffet is provided each morning plus a complimentary reception in the evening, when cocktails & snacks are served. For recreation, guests may use the exercise room, outdoor pool, hot tub or ping pong table. There are plenty of nearby restaurants amongst the surrounding office buildings, and to reach other attractions I-805 is just 1.5 miles west along Mira Mesa Blvd.