Click on a hotel for reservations. The hotels featured are either right beside the interstate exit or at most half a mile from it. I-45 begins in Galveston, passes through Houston, Conroe, Huntsville and Corsicana before terminating in downtown Dallas.
All Texas interstates: I-2, I-10, I-20, I-27, I-30, I-35, I-35E, I-35W, I-37, I-40, I-44, I-45.
All Texas interstates: I-2, I-10, I-20, I-27, I-30, I-35, I-35E, I-35W, I-37, I-40, I-44, I-45.
Please refer to the disclosure notice for information about the affiliate (commissionable) links on this page.
| Exit | Roads | City | Hotels |
| TX 87 (Broadway, Avenue J) | Galveston | ||
| 1A | Spur 342 (61st Street), 71st Street | Galveston | ★★★★★ SpringHill Suites Galveston Island ★★★★★ Candlewood Suites Galveston ★★★★★ Sleep Inn & Suites Galveston Island |
| 1B | 71st Street | Galveston | |
| 1C | FM 188 (Teichman Road), TX 275 (Harborside Drive) | Galveston | ★★★★★ Howard Johnson by Wyndham Galveston |
| 4 | Tiki Drive | Tiki Island | |
| 5 | Frontage Road | ||
| 6 | Frontage Road | Bayou Vista | |
| 7A | TX 3 north, TX 146 north | Bayou Vista | |
| 7B | TX 6 west | Bayou Vista | |
| 7C | Frontage Road | Bayou Vista | |
| 7 | TX 6, TX 146 - Texas City | Bayou Vista | |
| 8 | Frontage Road | La Marque | |
| 9 | Frontage Road | La Marque | |
| 10 | FM 519 (Main Street) | La Marque | |
| 11 | Vauthier Road | La Marque | |
| 12 | FM 1765 (Texas Avenue) | Texas City | |
| 13 | Century Blvd, Delany Road | Texas City |
★★★★★ Super 8 by Wyndham La Marque Texas City Area |
| 15 | FM 1764, FM 2004 (Mall of the Mainland Parkway) | Texas City | ★★★★★ Holiday Inn Express Hotel & Suites Texas City ★★★★★ SureStay by Best Western Texas City I-45 |
| 16 | FM 1764 east (Emmett F. Lowry Expressway) | Texas City | ★★★★★ Comfort Inn & Suites Texas City ★★★★★ Quality Inn Texas City |
| 17 | Holland Road, Hughes Road | Texas City | ★★★★★ SpringHill Suites Texas City |
| 19 | FM 517, Hughes Road | Dickinson | ★★★★★ Days Inn by Wyndham Dickinson TX |
| 20 | FM 646 (16th Street) | League City | ★★★★★ Hampton Inn & Suites Houston-League City ★★★★★ Candlewood Suites League City ★★★★★ Fairfield Inn & Suites Houston League City |
| 22 | Calder Drive, Brittany Bay Boulevard | League City | |
| 23 | FM 518 (Main Street) | League City | ★★★★★ SpringHill Suites Houston Clear Lake/Webster ★★★★★ Super 8 by Wyndham League City Kemah Area |
| 25 | FM 528, NASA Parkway | Webster | ★★★★★ Days Inn & Suites by Wyndham NASA Space Center Houston |
| 26 | Bay Area Boulevard | Webster | ★★★★★ Hilton Garden Inn Houston/Clear Lake NASA ★★★★★ Holiday Inn Express Hotel & Suites Houston Space Center - Clear Lane ★★★★★ Best Western Webster Hotel, NASA ★★★★★ Comfort Suites Webster |
| 27 | El Dorado Boulevard | Friendswood, Webster | ★★★★★ Residence Inn Houston NASA/Clear Lake |
| 29 | FM 2351 (Clear Lake City Boulevard) | Houston | |
| 30 | FM 1959 (Dixie Farm Road) | Houston | |
| 31 | Beltway 8 (Frontage Road), FM 2553 (Scarsdale Boulevard) | Houston | |
| 32 | Sam Houston Tollway | Houston | |
| 33 | Beltway 8 (Frontage Road), Fuqua Street | Houston | |
| 34 | Almeda-Genoa Road, South Shaver Road | Houston | ★★★★★ Baymont by Wyndham Houston Hobby Airport ★★★★★ Super 8 by Wyndham Houston Hobby Airport South |
| 35 | Clearwood Drive, Edgebrook Drive | Houston | |
| 36 | Airport Boulevard, College Avenue | Houston | ★★★★★ Marriott Houston Hobby Airport ★★★★★ Courtyard Houston/Hobby Airport ★★★★★ Hilton Garden Inn Houston Hobby Airport ★★★★★ TownePlace Suites Houston Hobby Airport ★★★★★ SpringHill Suites Houston Hobby Airport ★★★★★ Wyndham Houston Hobby Airport ★★★★★ Holiday Inn Express & Suites Houston SE - Hobby Airport Area ★★★★★ GreenTree Inn & Suites Houston Hobby Airport ★★★★★ Howard Johnson by Wyndham Houston Hobby Airport ★★★★★ Best Western Plus Hobby Airport Inn & Suites ★★★★★ Days Inn & Suites by Wyndham Houston Hobby Airport ★★★★★ Spark by Hilton Houston Hobby Airport ★★★★★ Travelodge by Wyndham Houston Hobby Airport |
| 38 | TX 3 (Monroe Road), Bellfort Avenue | Houston | ★★★★★ Fairfield Inn & Suites Houston Hobby Airport |
| 38B | Howard Drive, Bellfort Avenue | Houston | |
| 39 | Park Place Boulevard, Broadway Boulevard | Houston | |
| 40A | Frontage Road | Houston | |
| 40B | I-610 east to TX 225 | Houston | |
| 40B | I-610, TX 35 south to TX 225 | Houston | |
| 40C | I-610 west | Houston | |
| 41A | Woodridge Drive | Houston | |
| 41B | Griggs Road, Broad Street | Houston | |
| 42 | US 90 Alt. (South Wayside Drive) | Houston | |
| 43A | Telephone Road | Houston | |
| 43B | Tellepsen Street | Houston | |
| 44A | Elgin Street, Lockwood Drive, Cullen Boulevard | Houston | |
| 44B | Spur 5 south | Houston | |
| 44C | Cullen Boulevard | Houston | |
| 45 | Scott Street | Houston | ★★★★★ Baymont by Wyndham Houston North |
| 46 | I-69, US 59, TX 288 south | Houston | |
| 47A | Allen Parkway | Houston | ★★★★★ Holiday Inn Houston Downtown |
| 47B | Houston Avenue, Memorial Drive | Houston | ★★★★★ Holiday Inn Express Hotel & Suites Houston-Downtown Convention Center |
| 47C | McKinney Street | Houston | ★★★★★ JW Marriott Houston Downtown |
| 47D | Dallas Street, Pierce Street | Houston | ★★★★★ Embassy Suites Houston Downtown ★★★★★ Best Western Plus Downtown Inn and Suites |
| 48 | Interstate 10 (US 90) - exit 768 | Houston | |
| 49A | Quitman Street | Houston | |
| 49B | North Main Street, Houston Avenue | Houston | ★★★★★ Holiday Inn Express & Suites Houston - N Downtown |
| 50A | Patton Street | Houston | ★★★★★ Sleep Inn & Suites Houston |
| 50B | Cavalcade Street, Link Road | Houston | ★★★★★ Heights House Hotel, Ascend Hotel Collection |
| 51 | I-610 | Houston | |
| 52A | Frontage Road | Houston | |
| 52B | Crosstimbers Road | Houston | |
| 53 | Airline Drive | Houston | |
| 54 | Tidwell Road | Houston | |
| 55A | Parker Road, Yale Street | Houston | |
| 55B | Little York Road | Houston | |
| 56A | Canino Road | Houston | |
| 56B | Spur 261 (North Shepherd Drive), Little York Road | Houston | |
| 57A | Gulf Bank Road | Houston | |
| 57B | TX 249 (West Mount Houston Road) | Houston | |
| 59 | West Road | Houston | ★★★★★ Comfort Inn & Suites Houston I-45 North - IAH ★★★★★ Days Inn & Suites by Wyndham HoustonNorth/Adine |
| 60A | FM 525 (Aldine Bender Road), Fallbrook Road | Houston | ★★★★★ Holiday Inn Express & Suites Houston Intercontinental Airport |
| 60B | Beltway 8 (Frontage Road) | Houston | |
| 60B | Beltway 8 east, Sam Houston Tollway west | Houston | |
| 61 | Greens Road | Houston | |
| 62 | Kuykendahl Road, Rankin Road, Ryan Drive | Houston | |
| 63 | Airtex Drive | Houston | ★★★★★ SpringHill Suites Houston I-45 North ★★★★★ Holiday Inn Express Hotel & Suites Houston North Intercontinental ★★★★★ Best Western Greenspoint Inn & Suites ★★★★★ Suburban Studios Houston North I-45 |
| 64 | Richey Road | Houston | ★★★★★ Super 8 by Wyndham Houston North I-45 |
| 66A | FM 1960 (Cypress Creek Parkway) | Houston | ★★★★★ Comfort Inn & Suites Houston ★★★★★ Quality Suites Houston North ★★★★★ Days Inn by Wyndham & Suites Houston North/FM 1960 |
| 66B | Hollow Tree Street, Paramatta Lane | Houston | |
| 68 | Cypresswood Drive, Holzwarth Road, Louetta Road | Houston | ★★★★★ Clarion Pointe Spring ★★★★★ Candlewood Suites Houston - Spring ★★★★★ Best Western Plus Spring Inn & Suites ★★★★★ Comfort Suites Spring |
| 70A | FM 2920 | Spring | |
| 70B | Spring Stuebner Road | ||
| 72B | Hardy Toll Road south | ||
| 72A | Springwoods Village Parkway | Spring | ★★★★★ Houston CityPlace Marriott at Springwoods Village ★★★★★ Hilton Garden Inn North Houston Spring ★★★★★ SureStay Hotel by Best Western Spring North Houston |
| 73 | Rayford Road, Sawdust Road | Spring, The Woodlands | ★★★★★ Hotel Indigo Houston North - Spring ★★★★★ Homewood Suites by Hilton The Woodlands/Springwoods Village ★★★★★ Holiday Inn Express Hotel & Suites The Woodlands ★★★★★ Fairfield Inn & Suites Houston North/Spring ★★★★★ Super 8 by Wyndham Spring |
| 76 | Robinson Road, Woodlands Parkway | The Woodlands | ★★★★★ Marriott Woodlands Waterway Hotel & Convention Center ★★★★★ Residence Inn Houston The Woodlands II |
| 77 | Lake Woodlands Drive, Research Forest Drive, Tamina Road | Shenandoah, The Woodlands |
★★★★★ EVEN Hotels Shenandoah - The Woodlands ★★★★★ Hampton Inn & Suites by Hilton Shenandoah The Woodlands ★★★★★ Aloft Shenandoah - Near the Woodlands ★★★★★ Holiday Inn Shenandoah-The Woodlands ★★★★★ Courtyard Houston The Woodlands ★★★★★ Courtyard Conroe ★★★★★ Residence Inn Houston The Woodlands I ★★★★★ Homewood Suites by Hilton Houston-The Woodlands ★★★★★ Super 8 by Wyndham The Woodlands North |
| 79 | TX 242 (College Park Drive, Needham Road) | Shenandoah, The Woodlands |
★★★★★ Hampton Inn & Suites North Houston Spring ★★★★★ TownePlace Suites Houston The Woodlands ★★★★★ SpringHill Suites Houston The Woodlands ★★★★★ Candlewood Suites Houston (The Woodlands) ★★★★★ Comfort Suites Shenandoah ★★★★★ Best Western The Woodlands ★★★★★ Fairfield Inn & Suites Houston The Woodlands ★★★★★ Days Inn by Wyndham Shenandoah |
| 81 | FM 1488 | ||
| 83 | Crighton Road, Camp Strake Road, River Plantation Drive | Conroe | |
| 84 | TX 75 north (Frazier Street), Loop 336 | Conroe | ★★★★★ Hampton Inn & Suites Conroe I-45 North |
| 85 | FM 2854, Gladstell Street | Conroe | ★★★★★ Comfort Inn Conroe |
| 87 | TX 105, FM 2854 (Davis Street) | Conroe | |
| 88 | Loop 336 (Cartwright Road) | Conroe | ★★★★★ Holiday Inn Express Hotel & Suites Conroe I-45 North ★★★★★ SureStay Studio by Best Western Conroe Downtown |
| 90 | FM 3083 (Teas Nursery Road) | Conroe | ★★★★★ Homewood Suites by Hilton Conroe ★★★★★ TownePlace Suites Houston Conroe ★★★★★ Fairfield Inn & Suites Houston Conroe |
| 91 | League Line Road | ★★★★★ Comfort Inn Conroe ★★★★★ Days Inn by Wyndham Conroe | |
| 92 | FM 830 (Seven Coves Drive) | ||
| 94 | FM 1097 (Montgomery Road) | Willis | |
| 95 | Longstreet Road | Willis | |
| 98 | TX 75, Shepard Hill Road, Danville Road | ||
| 102 | TX 150, FM 1374, FM 1375 | New Waverly | |
| 109 | PR 40 - Huntsville State Park | ||
| 112 | TX 75 | Huntsville | |
| 113 | TX 19 - Riverside, Crockett | Huntsville | |
| 114 | FM 1374 (Montgomery Road) | Huntsville | ★★★★★ Comfort Inn & Suites Huntsville ★★★★★ Quality Suites Huntsville ★★★★★ Super 8 by Wyndham Huntsville |
| 116 | US 190 east (11th Street), TX 30 | Huntsville | ★★★★★ Hampton Inn & Suites Huntsville ★★★★★ Home2 Suites by Hilton Huntsville ★★★★★ Holiday Inn Express Hotel & Suites Huntsville ★★★★★ Best Western Huntsville Inn & Suites ★★★★★ Fairfield Inn & Suites Huntsville ★★★★★ Days Inn & Suites by Wyndham Huntsville ★★★★★ Rodeway Inn Huntsville |
| 118 | TX 75, FM 1791 | Huntsville | |
| 123 | FM 1696 | ||
| 132 | FM 2989 | ||
| 136 | Spur 67 | ||
| 142 | US 190 west (Main Street), TX 21 | Madisonville | ★★★★★ Best Western Executive Inn & Suites ★★★★★ Quality Inn Madisonville ★★★★★ Days Inn & Suites by Wyndham Madisonville |
| 146 | TX 75 | Madisonville | |
| 152 | TX OSR, County Line Road | ||
| 156 | FM 977 | Leona | |
| 164 | TX 7 (St Marys Street) | Centerville | ★★★★★ Days Inn by Wyndham Centerville |
| 178 | US 79 (Commerce Street) | Buffalo | ★★★★★ Hampton Inn & Suites Buffalo ★★★★★ Quality Inn Buffalo ★★★★★ Super 8 by Wyndham Buffalo |
| 180 | TX 164 (Donie Road) | Buffalo | |
| 189 | TX 179 | Drew | |
| 197 | US 84 (Teague Street) | Fairfield | ★★★★★ Holiday Inn Express Hotel & Suites Fairfield-North ★★★★★ Super 8 by Wyndham Fairfield, TX |
| 198 | FM 27 (Commerce Street) | Fairfield | |
| 206 | FM 833 | ||
| 211 | FM 80 (Houston Street) | Streetman | |
| 213 | TX 75, FM 246 | Streetman | |
| 218 | FM 1394 | Richland | |
| 219A | TX 14 | Richland | |
| 219B | Frontage Road | Richland | |
| 220 | Frontage Road | ||
| 221 | Frontage Road | ||
| 225 | FM 739 | Angus, Mustang | |
| 228A | 15th Street | Corsicana | |
| 228B | I-45 Bus north, Frontage Road | Corsicana | |
| 229 | US 287 south | Corsicana | ★★★★★ Hampton Inn & Suites Corsicana ★★★★★ Holiday Inn Express Hotel & Suites Corsicana I-45 ★★★★★ Quality Lodge Corsicana |
| 231 | TX 31 (M L King Jr Boulevard) | Corsicana | ★★★★★ Best Western Plus Executive Inn ★★★★★ Comfort Inn Corsicana ★★★★★ Super 8 by Wyndham Corsicana |
| 232 | Roane Road, East 5th Avenue | Corsicana | |
| 235B | I-45 Bus south | Corsicana | |
| 235A | Frontage Road | Corsicana | |
| 237 | Frontage Road | ||
| 238 | FM 1603 | ||
| 239 | FM 1126 | ||
| 242 | Calhoun Street | Rice | |
| 243 | Frontage Road | ||
| 244 | FM 1182 | ||
| 246 | FM 1183 | Alma | |
| 247 | US 287 north | ||
| 249 | I-45 Bus north, FM 85 - Ennis | ||
| 251A | FM 1181 (Creechville Road) | Ennis | ★★★★★ Comfort Suites Ennis |
| 251B | TX 34 (Ennis Avenue) | Ennis | ★★★★★ Holiday Inn Express Hotel & Suites Ennis ★★★★★ Quality Inn Ennis |
| 253 | I-45 Bus south - Ennis | Ennis | |
| 255 | FM 879 | Garrett | |
| 258 | I-45 Bus north, Parker Hill Road | Palmer | |
| 259 | FM 813 (Jefferson Street) | Palmer | |
| 260 | I-45 Bus south, Frontage Road | Palmer | |
| 262 | Frontage Road | ||
| 263A | Loop 561 | Trumbull | |
| 263B | Frontage Road | ||
| 264 | Frontage Road | ||
| 265 | I-45 Bus north | Ferris | |
| 266 | FM 660 (5th Street) | Ferris | |
| 267 | Frontage Road | Ferris | |
| 268 | I-45 Bus south, Malloy Bridge Road | Ferris | |
| 269 | Mars Road | ||
| 270 | Belt Line Road | Wilmer | |
| 271 | Pleasant Run Road | Wilmer | |
| 272 | Fulghum Road | Hutchins | |
| 273 | Wintergreen Road | Hutchins | |
| 274 | Dowdy Ferry Road, Palestine Street | Hutchins | |
| 275 | TX 310 north | Dallas | |
| 276 | Interstate 20 - exit 473 | Dallas | |
| 277 | Simpson Stuart Road | Dallas | |
| 279 | Loop 12 | Dallas | |
| 280 | Illinois Avenue, Linfield Street | Dallas | |
| 281 | Overton Road | Dallas | |
| 283A | Lamar Street | Dallas | |
| 283B | Pennsylvania Avenue, Martin Luther King, Jr. Boulevard | Dallas | |
| 283B | US 175 east, Martin Luther King, Jr. Boulevard - Kaufman | Dallas | |
| 284A | Interstate 30 - exit 46 | Dallas | |
| 284B | Main Street, Elm Street | Dallas | |
| 284C | Live Oak Street (Central Expressway south) | Dallas | |
| 285 | Bryan Street east | Dallas | |
| 285 | Ross Avenue | Dallas | |
| 286A | To I-35E (Spur 366) | Dallas | |
| US 75 north (Central Expressway) | Dallas |
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