At 993 S Main Street, The Best Western Inn of Cottonwood, AZ, has quite a central location, at the northwest corner of the junction of highway 279 with US 89 - within a mile of supermarkets and a Wal-Mart in Cottonwood, and 3 miles from the main natural attraction in the area, Tuzigoot National Monument. The 77 rooms of the AAA Three Diamond-rated Best Western include several casitas - more exclusive accommodation with patios, refrigerators and separate entrances - and many have relaxing views over the hotel's central garden, outdoor pool and hot tub. The building is 200 feet away from the main road and so nice and quiet; the other main facilities are free continental breakfast, 24 hour front desk, and a meeting room. Rates are quite reasonable and the staff very friendly.

The Quality Inn hotel in Cottonwood is situated towards the west edge of town, between the Verde Valley Medical Center and Cottonwood Airport, on the south side of US 89 (301 W). There is one restaurant within the hotel (Franco's), others nearby, and the Verde Shopping Center is 1.3 miles away. An attractive landscaped garden greets guests at the front of the hotel, though the accommodation block is at the rear, in the middle of a large carpark; there are 51 spacious rooms, some overlooking the outdoor pool & hot tub. The inn has conference facilities catering for up to 300 people.