The Holiday Inn Express is by general consensus the best of the small selection of hotels in La Junta, CO, offering 59 clean rooms, a pool/hot tub, exercise room, meeting/event facilities, and free hot breakfast. Pets are welcome for a small fee. The hotel has a semi-rural location at the west edge of town along US 50, close to the Arkansas River; there are a couple of restaurants nearby though a better selection is found a mile or two east towards the center of La Junta. The main recreation site in this part of Colorado is John Martin Reservoir, 25 miles further east.

Hampton Inn-La Junta opened summer 2009 on the west side of town along the southern US 50 frontage road, in a lightly developed area close to a few restaurants and shops including Wal-Mart. There are 62 rooms available, all clean, modern and welcoming, and equipped with a microwave. Free hot breakfast is served each morning, or a free snack bag for guests in a hurry. A fitness room and indoor pool are the two leisure facilities, while a business center and boardroom are available for those here to work.