Along El Camino Real half way between Palo Alto and the neighboring town of Mountain View, the 194 room Crowne Plaza Palo Alto occupies a large, wooded site surrounded by private residences, with its accommodation blocks quite far from the highway ensuring a quiet night's sleep. Although primarily a business hotel, catering to the nearby Silicon Valley technology companies, the attractions of San Jose and San Francisco are an easy drive away along US 101. The many full service amenities of the Crowne Plaza include a beautiful lobby, a large outdoor pool & hot tub, a restaurant, two bars, gift shop, fitness center, and a wide range of facilities for business & meetings.

Right next to the Quality Inn at 3945 El Camino Real, the Comfort Inn offers 70 well maintained rooms, looked after by friendly, helpful staff. The inn is 2 miles east of the center of Palo Alto and 2.5 miles from Highway 101, closest exit being 402, the Oregon Expressway. The rooms are on 2 floors, in one long block facing either the parking area or an adjacent building, so the views are not especially exciting, but the neighborhood has a good selection of restaurants.

Quality Inn Palo Alto is a fairly standard motel-style establishment along the main street through town (El Camino Real), within 2 miles of both Stanford University and the San Antonio Shopping Center. There are 2 floors and 52 clean, exterior-corridor rooms, all containing a refrigerator and a microwave. Continental breakfast (free) is available on site, with several adjacent restaurants to provide other meals.