Jackson's Holiday Inn Express is a clean, new building on the corner of Clinton Rd and Sutter St (highway 49), towards the south side of town and 10 minutes walk (or less) from all major amenities, which include a museum, movie theater, supermarket and a selection of restaurants. The hotel has 51 spacious rooms & suites, a fitness center, guest laundry and breakfast bar, though no pool.

The 119 room Best Western Amador Inn of Jackson, CA, occupies quite a large site near the center of town, alongside the main road (CA 49) in a wooded neighborhood with views over the Sierra Nevada foothills. The nearby countryside offers many interesting sites within 30 miles including wineries, lakes, old gold mines, caves and golf courses. The inn has a full service Denny's restaurant on the premises and is less than 1/4 mile from various other diners, plus several stores. For leisure, the hotel offers a recently renovated outdoor pool & spa.