Click on a city for full hotel listings and location maps, or a hotel for reservations. The hotels featured are either right beside the interstate exit or at most half a mile from it. I-8 is the southernmost interstate highway in California, linking San Diego with Yuma, Arizona.

California highways: I-5, I-8, I-10, I-15, I-40, I-80, US 101.

Exit	Roads	City	Hotels
0	Nimitz Boulevard, Sunset Cliffs Boulevard	San Diego - Mission Bay	Hyatt Regency Mission Bay Spa & Marina
1	West Mission Bay Drive, Sports Arena Boulevard	San Diego - Mission Bay	Holiday Inn Express San Diego-Sea World Area Ramada by Wyndham Sea World
2	Interstate 5 (north) - exit 20	San Diego - Mission Bay
2A	Interstate 5 (south) - exit 20	San Diego
2B	Rosecrans Street	San Diego
2C	Morena Boulevard	San Diego - Mission Bay	Hilton Garden Inn San Diego Old Town/SeaWorld Area
3	Taylor Street, Hotel Circle	San Diego - Mission Valley	Crowne Plaza San Diego - Mission Valley Residence Inn San Diego Mission Valley Comfort Inn & Suites San Diego Zoo/Sea World Area Hampton Inn San Diego/Mission Valley Homewood Suites by Hilton San Diego Hotel Circle/Sea World Area Howard Johnson by Wyndham San Diego Hotel Circle Motel 6 San Diego - Hotel Circle
4A	Hotel Circle	San Diego - Mission Valley	Courtyard San Diego Mission Valley/Hotel Circle Holiday Inn Express & Suites San Diego NE - Hotel Circle Best Western Seven Seas DoubleTree Club Hotel San Diego Candlewood Suites San Diego North Days Hotel by Wyndham San Diego Hotel Circle near Seaworld Super 8 by Wyndham San Diego Hotel Circle
4	CA 163 (Cabrillo Freeway)	San Diego - Mission Valley
5	Mission Center Road, Auto Circle	San Diego - Mission Valley	Comfort Suites Mission Valley Hilton San Diego Mission Valley Homewood Suites by Hilton San Diego Mission Valley/Zoo
6A	Texas Street, Qualcomm Way	San Diego - Mission Valley	SpringHill Suites San Diego Mission Valley
6B	I-805	San Diego - Mission Valley	Marriott San Diego Mission Valley
7	Interstate 15, CA 15 - exit 6B	San Diego - Mission Valley
8	Mission Gorge Road, Fairmount Avenue	San Diego - Mission Valley
9	Waring Road	San Diego - Mission Valley	Quality Inn San Diego near Qualcomm Stadium Days Inn by Wyndham Mission Valley Qualcomm Stadium SDSU
10	College Avenue	San Diego
11	Lake Murray Blvd, 70th Street	La Mesa
12	Fletcher Parkway, Baltimore Drive	La Mesa	Holiday Inn San Diego-La Mesa Motel 6 San Diego - La Mesa
13A	Spring Street, El Cajon Boulevard	La Mesa
13B	Jackson Drive, Grossmont Boulevard	La Mesa
14B	La Mesa Boulevard, Grossmont Center Drive	La Mesa
14A	CA 125 to CA 94	La Mesa
14C	Severin Drive, Fuerte Drive	La Mesa	Best Western Plus La Mesa San Diego
15	El Cajon Boulevard (I-8 Bus)	El Cajon	Quality Inn & Suites San Diego East Rodeway Inn & Suites San Diego East
16	Main Street	El Cajon	SureStay Plus Hotel by Best Western El Cajon
17A	Johnson Avenue	El Cajon
17	CA 67, Magnolia Avenue	El Cajon	Courtyard San Diego El Cajon Super 8 by Wyndham El Cajon Motel 6 San Diego - El Cajon
18	Mollison Avenue	El Cajon	Best Western Continental Inn Quality Inn El Cajon Days Inn by Wyndham El Cajon East San Diego Econo Lodge Inn & Suites El Cajon San Diego East
19	2nd Street	El Cajon
20A	East Main Street (I-8 Bus)	El Cajon
20B	Greenfield Drive	El Cajon
22	Los Coches Road	Lakeside
23	Lake Jennings Park Road
27	Dunbar Lane - Harbison Canyon
30	Tavern Road (I-8 Bus)	Alpine
33	Willows Road, Alpine Boulevard (I-8 Bus)	Alpine
36	East Willows Road
40	CA 79 north (Japatul Road)
45	Pine Valley Road
47	Sunrise Highway (CR S1)
51	Buckman Springs Road
54	Kitchen Creek Road
61	Crestwood Road
65	CA 94	Boulevard
73	Jacumba
77	In-Ko-Pah Park Road
80	Mountain Springs Road
87	CA 98
89	Imperial Highway (CR S2)	Ocotillo
101	Dunaway Road
107	Drew Road (CR S29)	Seeley
111	Forrester Road (CR S30)
114	Imperial Avenue (I-8 Bus)	El Centro	Clarion Inn El Centro Super 8 by Wyndham El Centro Travelodge by Wyndham El Centro
115	CA 86 (4th Street, I-8 Bus)	El Centro	Holiday Inn Express Hotel & Suites El Centro Best Western John Jay Inn Comfort Inn & Suites El Centro MainStay Suites El Centro I-8 Motel 6 El Centro
116	Dogwood Road (CR S31)	El Centro	Hampton Inn El Centro
118	CA 111
120	Bowker Road
125	CA 7 (Orchard Road, CR S32)	Holtville
128	Bonds Corner Road
131	CA 115 (Van Der Linden Road)
143	CA 98
146	Brock Research Center Road
151	Gordons Well
156	Grays Well Road
159	Ogilby Road (CR S34)
164	Sidewinder Road	Felicity
166	CA 186 south (Algodones Road)	Andrade
170	Winterhaven Drive (CR S24, I-8 Bus)	Winterhaven
172	Winterhaven Drive, Fourth Avenue (I-8 Bus)	Winterhaven
	(mile 172.5 - Arizona state line)
	Interstate 8 in Arizona