Holiday Inn Express Chula Vista is a new-looking, 3 floor building surrounded by palm trees next to I-805 (exit 3; Main St), close to Otay, Castle Park and Otay Mesa as well as Chula Vista, and offers perhaps the best lodging of the somewhat limited choice of hotels south of San Diego. The Mexican border is 4 miles further south, while two of the main area attractions (Knotts Soak City USA Waterpark and Coors Amphitheatre) are 2.3 miles east. For relaxation, the Holiday Inn Express has an outdoor pool, hot tub and fitness center; other amenities are guest laundry, a microwave/refrigerator in each room, and the free Express Start continental breakfast.

In downtown Chula Vista, CA (at 710 E St), Best Western South Bay Inn offers 76 rooms in a 2 floor, motel-style building with good local transport connections - I-5 is one block west, the South Bay Freeway a short distance north, and the San Diego Trolley stops right next door. Also within a few minute's walk are several restaurants including Denny's. The recently renovated inn now has added amenities of a deluxe suite wing, a business center, fitness center and guest laundry, complimenting the existing outdoor pool and on-site cafe, serving breakfast & lunch.

The smaller of the two Best Western hotels in Chula Vista is located along busy Broadway street, a few blocks south of the town center and half a mile east of interstate 5 (exit 7A) - about half way between San Diego and the border with Mexico. The 3 storey, 52 room building has quite a small frontage, lined with palm plants, with a driveway to an inner courtyard/parking area, next to an outdoor pool & hot tub. Free continental breakfast is served. The nearest shopping mall is the Chula Vista Center, one mile north along Broadway.

Chula Vista's Comfort Inn is the newest hotel in town, an impressive four storey building lined with the obligatory palm trees, situated on E Street, a few blocks west of the town center and within easy reach of I-5, I-805 & the South Bay Freeway. All the rooms contain a microwave, refrigerator, coffee maker and ironing facilities. The two main leisure amenities are a fitness center and an outdoor heated pool, at the rear of the hotel well away from the main road. The hotel serves free deluxe continental breakfast and has a convenience store though no restaurant; the nearest diners are one block east and west.